NasoNeb® Nasal Nebulizer

Backed by peer-reviewed scientific data, the NasoNeb® Nasal Nebulizer is the fast, convenient solution for complete drug delivery coating to the nasal and paranasal sinus cavities providing low-volume, high concentration delivery. The NasoNeb® Nasal Nebulizer delivers large particles that are readily filtered by the nasal passages to ensure a large percentage of medication is delivered only to the target organ, avoiding the lungs. These particles are delivered via a positive pressure airstream that coats the entire sino-nasal cavity with the medication.1, 2

People who may benefit from topical pharmaceutical therapy delivered by the NasoNeb® Nasal Nebulizer include but are not limited to the following:

  • Post-operative sinus surgery patients with recurrent nasal polyps
  • Post-sinus surgery patients with chronic nasal crusting and infection
  • Patients with bacterial or fungal infections who are not candidates for sinus surgery
  • Patients with other sinus conditions
  • Patients suffering from recurrent allergic rhinitis

Doug’s Compounding Pharmacy prepares customized medications for nasal nebulization using Loxasperse, an innovative powder base. A unique proprietary blend of micronized xylitol and polymers, Loxasperse is designed to enhance dispersability and solubility of actives and has been shown to increase activity against biofilms. By combining multiple drugs into a single dosage form, Loxasperse can simplify nasal therapy regimens.

To learn more about NasoNeb® and Loxasperse, contact Doug’s Compounding Pharmacy.

  1. Manes RP, Tong L, Batra PS. “Prospective evaluation of aerosol delivery by a powered nasal nebulizer in the cadaver model” Int Forum Allergy Rhinol, 2011; 1:366–371
  2. Yuri M. Gelfand, MD; Samer Fakhri, MD; Amber Luong, MD, PhD; Seth J. Isaacs, MD & Martin J. Citardi, MD: “A Comparative Study of the Distribution of Normal Saline Delivered by Large Particle Nebulizer vs. Large Volume/Low Pressure Squeeze Bottle” 56th Annual Meeting of the American Rhinologic Society, September 25, 2010, page 38
  3. PCCA 2013 Loxasperse. Available at
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